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1. without considering He will do anything, no matter how unfair, to win an election.
Usage notes: usually followed by how, as in the example, or by who, what, or which: He'll say what he thinks, no matter who you are. She goes out running no matter what the weather is like.
2. (spoken) it is not important You never thought about it, did you? Well, no matter.
no matter(slightly formal)
something that you say which means that a problem is not important It's raining, but no matter, I'll take the dog for a walk anyway.
1. It's not important, as in She wasn't home when I came by, but no matter. [Mid-1500s]
2. Also, no matter what. Regardless, it makes no difference, as in No matter what I say, she'll do what she likes, or The car must be repaired, no matter what. [Mid-1500s]
Regardless of: "Yet there isn't a train I wouldn't take, / No matter where it's going" (Edna St. Vincent Millay).