repair of UV-, methyl methanesulfonate- and N-methyl-N-nitrosourea-induced DNA damage in Chinese hamster ovary cells.
Even the sulforaphane precursor dramatically inhibits
chemically induced cancers in rats, Talalay's team reports in the Sept.
Abstract Number 1116: Bone-targeted rapamycin analogs inhibit
osteolysis and tumor growth in a PC-3-GFP intratibial bone cancer model in nude mice
By using our kinase profiling technology to identify existing drugs in development that inhibit
these mutations, we've provided data to guide the development of next-generation cancer drugs and hopefully supplied a more immediate solution by pointing to existing drug candidates that may counter cancer patients' resistance issues.
Ramon Flick, also of the UTMB, is titled "Antisense Morpholino Oligomers Directed Against Bunyavirus Genome Segments Inhibit
Replication and Proliferation.
The drug inhibits
production of tumor necrosis factor alpha (TNF-[alpha]) by white blood cells called monocytes, scientists at Rockefeller University in New York and their colleagues reported in 1991.
Study results suggest that NEUGENES produce a significant decrease in cell viability along with a specific decrease in XIAP levels in cells pretreated with a NEUGENE designed to inhibit
XIAP in a prostate cancer model.
The other two, the antibiotic bacitracin and antibodies against PDI, specifically inhibit
Nasdaq:AVII), today announced the publication of two articles describing preclinical studies in which its NEUGENE(R) antisense drugs were used to inhibit
dengue virus and West Nile virus (WNV) infection.
Albert Einstein College of Medicine of Yeshiva University (Bronx, NY) has patented peptides comprising an Rpt1 domain of an INI1/hSNF5 which inhibit
HIV-1 production in a human cell, and vectors encoding those peptides.
A seaweed derivative that's commonly added to baby food, lubricants, and other consumer products as a thickening agent can inhibit
the virus that causes cervical cancer and genital warts.
These IFN-stimulated genes inhibit
viral replication by many different mechanisms, including binding to viral nucleocapsids, translation inhibition, RNA degradation, RNA editing, and apoptosis induction.
The major point of our article (Luckenbach and Epel 2005) was that the musks inhibit
efflux (drug) transporters, which act as first lines of defense to pump potentially toxic substances out of cells.
Modern birth control pills are estrogen, which inhibit
implantation of the fertilized ovum into the uterus.
Irgaguard antimicrobials can inhibit
the growth of certain microorganisms, such as fungus, bacteria, algae, mold and mildew, which can cause deterioration, unpleasant odor formation and discoloration in elastomers and rubber applications, to protect the finished product, Irgaguard A is said to be an effective algaecide to inhibit
growth of algae and moss on treated articles in certain rubber applications such as roofing, camping accessories and SBS modified asphalt shingles.