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Fig. laughing very hard. Charlie had us in stitches with all his jokes. The movie sure was funny. I was in stitches!
laughing so much that it is difficult to control yourself The movie will keep you in stitches from beginning to end.
Laughing uncontrollably, as in Joke after joke had me in stitches. Although the precise idiom dates only from about 1930, Shakespeare had a similar expression in Twelfth Night (3:2): "If you desire the spleen, and will laugh yourselves into stitches, follow me." Stitches here refers to the sharp local pain (known as a stitch in the side) that can make one double over, much as a fit of laughter can.