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1. In baseball and softball, a hit that allows one to round all four bases and score, typically because the ball has been hit past the limits of the outfield. If Lamont can hit a home run, we'll win the game!
2. By extension, an action that is very successful. Our numbers have been down, so we really need to hit a home run this quarter in order to turn a profit for the year. It was an unexpected interview question, but I really feel like a hit a home run with it.
A highly successful achievement; also, doubling one's profits. For example, We scored a home run with that drug stock, buying it at 15 and selling at 30. This expression originated in the mid-1800s in baseball, where it refers to a pitched ball batted so far that the batter can round all three bases and reach home plate, scoring a run. Its figurative use dates from the mid-1900s.