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bane of life

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the bane of your life
someone or something that is always causing problems for you and upsetting you. I have a sister who's always getting into trouble and expecting me to sort her out. She's the bane of my life.
See also: life

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This is a very important gathering at a time when infectious diseases are making an unfortunate comeback in developed nations and remain the bane of life for millions in the emerging world," said Professor Davis.
 
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