touch with (something)

1. To bring something into light contact with someone or something. A noun or pronoun is used between "touch" and "with." He touched the electric fence with his bare hand and got an awful shock from it. A: "Here, let me wipe that muck off your face." B: "Blech! Please don't touch me with that disgusting handkerchief!"

2. To affect someone at a deep, emotional level with some action, performance, words, etc. A noun or pronoun is used between "touch" and "with." You really touched me with your kind words at the ceremony today. She was touched with the way the community rallied around her during the crisis.

touch someone or something with something

to bring something into contact with someone or something. Don't touch me with that filthy stick! I touched the snake with a stick to make sure it was dead. Wherever he touched himself with the leaf, his skin blistered.