lose (one's) buttons

To be or become mentally deficient, incompetent, or deranged; to become of unsound mind. My poor grandmother started losing her buttons after she had a stroke on her 84th birthday. I've been so sleep deprived lately that it feels like I'm losing my buttons!

lose one's buttons

see under have all one's buttons.

See also: button, lose

The American Heritage® Dictionary of Idioms by Christine Ammer. Copyright © 2003, 1997 by The Christine Ammer 1992 Trust. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

See also:

lose (one's) buttons
lose (one's) marbles
lose your marbles
lose all one's marbles
lose marbles
lose one's marbles
lose one's mind
lose your mind
lose (one's) mind
go off (one's) dot

All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.