go out of (one's) mind with (something)

go out of (one's) mind with (something)

To be irrational, senseless, or insane because of an extreme amount of some negative emotion or sensation. It rained the whole camping trip, and we started going out of minds with boredom being stuck in the tent all day. After yet another sleepless night, I feel like I'm going out of my mind with exhaustion. I'm starting to go out of my mind with frustration because no one listens to me around here!

See also: go, mind, of, out

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