experiment with (something)
1. Literally, to use something as a component in research or tests. We got approval to start experimenting with this new procedure on mice, so we can see how the procedure affects their islet cells. Sure, it's a compelling hypothesis, but I think you need to experiment with it some more. We're not real scientists, so why do we have to experiment with a frog for Bio class? So gross.
2. By extension, to try doing or using something new. I'm experimenting with basil tonight, even though I don't usually include it in this recipe. I just don't like the synth-heavy sound the band's experimenting with on this album. Honestly, I've never had any desire to experiment with drugs and alcohol.
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