at the forefront of (something)

In a position of highest importance or priority within the context of some specific area or realm. The new company I work for is at the forefront of medical innovation. I think some of their new instruments are going to revolutionize the field of medicine. My kids' safety is always a concern at the forefront of my mind. Did you know that new professor is at the forefront of genetics research? Yeah, he's supposedly doing revolutionary stuff.