Christmas disease


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Related to Christmas disease: haemophilia, Hemophilia C, Von Willebrand disease, Hæmophilia

Christmas disease

Hemophilia (or haemophilia) B, a blood-clotting disorder in which a mutation of the Factor IX gene leads to a deficiency of Factor IX (or Christmas factor), a serine protease of the coagulation system. Both the factor and the disease are named for Stephen Christmas (not the holiday), the first patient discovered to have the condition in 1952. We haven't let our daughter participate in any more physical sports since she was diagnosed with Christmas disease last year.
See also: Christmas, disease
References in periodicals archive ?
Hemophilia B, or Christmas Disease, is caused by a defect or deficiency of Factor IX.
Hemophilia B, also known as Christmas Disease, is caused by a deficiency of a blood plasma protein called factor IX that affects the clotting property of blood.
It is indicated for the prevention and control of bleeding in Factor IX deficiency, also known as hemophilia B or Christmas disease.